董志强 博士 教授 博士生导师
湖北省引进高层次人才。现任中国临床肿瘤学会（CSCO）·神经系统肿瘤专家委员会 副主任委员；中国微循环协会·肿瘤专业委员会 副主任委员；中国动物学会斑马鱼分会 理事；湖北神经科学学会 常务理事；湖北遗传学会 理事。长期致力于神经干细胞发育、脑损伤与再生调控机理研究。发表SCI论文50余篇；作为第一完成人，获得国家发明专利授权7项。主持多项国家自然科学基金，并获得湖北省重大研发计划项目、湖北省杰出青年基金资助。
研究方向
1. 神经干细胞体内发育调控的细胞和分子机制。
2. 脑卒中时的神经损伤机制与神经保护、神经再生。
3. 胶质瘤进展的细胞和分子机制。
代表性论文
1. Aixin Yu, Yiqi Wang, Chao Duan, Jun Qin, Miaomiao Liao, Haiyan Zhu, Junrong Lei, Jun Liu, Zehao Yang, Li Yu, Hui Gui, Jinxin Xin, Weiwei Tao, Wendai Bao*, Zhiqiang Dong*, Hypoxia-induced circPLOD2a/b promotes the aggressiveness of glioblastoma by suppressing XIRP1 through binding to HuR, Communications Biology, 2025 Jan 17;8(1):71. doi: 10.1038/s42003-025-07503-3.
2. Ruolin Zhang #, Sicheng Guo#, Jie Zhou#, Xiumei Lin, Ying Wang, Yiqi Wang, Muyang Li, Kaichen Zhao, Wendai Bao, Ke Shui, Chuanyu Liu, Chang Liu*, Zhiqiang Dong*, Monitoring of single-nucleus chromatin landscape of ischemic stroke in mouse cerebral cortex across time, Scientific Data. 2025 Jan 11;12(1):47. doi: 10.1038/s41597-025-04367-4.
3. Guangqiang Li, Ruolin Zhang, Keyu Chen, Jiawen Dong, Zhihao Yang, Hangyu Chen, Haipeng Wang, Hui Wang, Huali Lei, Wendai Bao, Min Zhang, Zhidong Xiao*, Liang Cheng*, Zhiqiang Dong*, Zinc sulfide nanoparticles serve as gas slow-release bioreactors for H2S therapy of ischemic stroke, Biomaterials, 2025 Apr: 315:122912. doi: 10.1016/j.biomaterials.2024.122912.
4. Xiaoyan Zhang, Povilas Dumčius, Roman Mikhaylov, Jiangfa Qi, Mercedes Stringer, Chao Sun, Van Dien Nguyen, You Zhou, Xianfang Sun, Dongfang Liang, Dongge Liu, Bing Yan, Xi Feng, Changjun Mei, Cong Xu, Mingqian Feng, Yongqing Fu, Aled Clayton, Ruicong Zhi, Liangfei Tian*, Zhiqiang Dong*, Xin Yang*，Surface Acoustic Wave-Enhanced Multi-View Acoustofluidic Rotation Cytometry (MARC) for Pre-Cytopathological Screening, Advanced Science, 2024 Aug 13:e2403574. doi: 10.1002/advs.202403574.
5. Yiqi Wang, Jinmei Zuo, Chao Duan2, Hao Peng, Jia Huang, Liang Zhao*, Li Zhang*, Zhiqiang Dong*, Large language models assisted multi-effect variants mining on cerebral cavernous malformation familial whole genome sequencing. Computational and Structural Biotechnology Journal, 2024 Feb 1;23: 843-858.
6. Shihui Ding, Xiquan Pang, Shaoxiang Luo, Huili Gao, Bo Li, Junqiu Yue, Jian Chen, Sheng Hu, Zepeng Tu, Dong He, Youyi Kuang, Zhiqiang Dong*, Min Zhang*. Dynamic RBM47 ISGylation confers broad immunoprotection against lung injury and tumorigenesis via TSC22D3 downregulation. Cell Death Discovery, 2023 Nov 30;9(1):430. doi: 10.1038/s41420-023-01736-z.
7. Ruolin Zhang, Weibing Mao, Lumeng Niu, Wendai Bao, Yiqi wang, Ying Wang, Yasha Zhu, Zhihao Yang, Jincao Chen, Jiawen Dong, Meng Cai, Zilong Yuan, Haikun Song, Guangqiang Li, Min Zhang, Nanxiang Xiong*, Jun Wei*, Zhiqiang Dong*, NSC-derived exosomes enhance therapeutic effects of NSC transplantation on cerebral ischemia in mice, Elife, 2023 Apr 27;12:e84493.
8. Guangqiang Li, Huali Lei, Yuqi Yang, Xiaoyan Zhong*, Fei Gong, Yuehan Gong, Yangkai Zhou, Yuqi Zhang, Haibin Shi, Zhidong Xiao, Zhiqiang Dong*, Liang Cheng*, Titanium Sulfide Nanosheets Serve as Cascade Bioreactors for H2S-Mediated Programmed Gas–Sonodynamic Cancer Therapy, Advanced Science, 2022 Oct;9(30):e2201069.
9. Carlos Sanchez-Priego#, Ruiqi Hu#, Linda L Boshans, Matthew Lalli, Justyna A Janas, Sarah E Williams, Zhiqiang Dong*, Nan Yang*, Mapping cis-regulatory elements in human neurons links psychiatric disease heritability and activity-regulated transcriptional programs, Cell Reports 2022 May 31;39(9):110877. doi: 10.1016/j.celrep.2022.110877.
10. Chang Liu#, Rui Li#, Young Li#, Xiumei Lin#, Kaichen Zhao#, Qun Liu#, Shuowen Wang； Xueqian Yang, Xuyang Shi, Yuting Ma, Chenyu Pei, Hui Wang, Wendai Bao, Junhou Hui, Michael Arman Berberoglu, Sunil Kumar Sahu, Kailong Ma, Guangyi Fan, Yuxiang Li, Shiping Liu, Ao Chen, Xun Xu*, Zhiqiang Dong*, Longqi Liu*, Spatiotemporal mapping of gene expression landscapes and developmental trajectories during zebrafish embryogenesis. Developmental Cell, 2022 May 23;57(10):1284-1298.
11. Guangqiang Li, Xiaoyan Zhong, Xianwen Wang, Fei Gong, Huali Lei, Yangkai Zhou, Chengfei Li, Zhidong Xiao*, Guoxi Ren, Liang Zhang, Zhiqiang Dong*, Zhuang Liu, Liang Cheng*, Titanium carbide nanosheets with defect structure for photothermal-enhanced sonodynamic therapy. Bioactive Materials, 2021 Jun 30;8:409-419.
12. Min Guo#, Minghai Ge#, Michael A. Berberoglu, Jie Zhou, Long Ma, Juan Yang, Qiyan Dong, Yanni Feng, Zhengxing Wu, Zhiqiang Dong. Dissecting Molecular and Circuit Mechanisms for Inhibition and Delayed Response of ASI Neurons during Nociceptive Stimulus. Cell Reports, 2018 Nov 13;25(7):1885-1897.
研究生招生专业
生物化学与分子生物学（学术型硕士）、神经生物学（学术型博士）、生物与医药（专业型硕士、博士）
主讲课程
神经生物学（本科生，英文）、生物医学前沿进展（研究生，英文）
联系方式
电子邮箱：dongz@mail.hzau.edu.cn
