专任教师

张晓妍

访问次数:发布日期:2019-09-19

张晓妍  博士、教授、博士生导师

研究方向

高尔基体在细胞自噬中的作用

教育经历

2001.9-2005.7河北大学,生物技术专业学士

2005.9-2010.7北京大学,细胞生物学专业博士

科研与学术工作经历

2010.8-2015.7美国密歇根大学,Research Fellow

2015.8-2019.7美国密歇根大学,Research Laboratory Specialist Intermediate

2019.8至今,华中农业大学,教授

发表论文

1. Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosis. Chen Q, Zhang X, Jiang

    Q, Clarke PR, Zhang C*.Cell Res. 2008;18(2):268-80.

2. Sequential phosphorylation of Nedd1 by Cdk1 and Plk1 is required for targeting of the gammaTuRC to the centrosome. Zhang X, Chen Q, Feng J, Hou J, Yang F, Liu J, Jiang

    Q, Zhang C*.J Cell Sci. 2009;122(Pt 13):2240-51.

3. Regulation of protein glycosylation and sorting by the Golgi matrix proteins GRASP55/65.Xiang Y#, Zhang X#, Nix DB, Katoh T, Aoki K, Tiemeyer M, Wang Y*.Nat Commun.

    2013;4:1659. (# 共同第一作者)

4. PCM1 recruits Plk1 to the pericentriolar matrix to promote primary cilia disassembly before mitotic entry. Wang G, Chen Q, Zhang X, Zhang B, Zhuo X, Liu J, Jiang Q, Zhang

    C*.J Cell Sci. 2013;126(Pt 6):1355-65.

5. Phosphorylation regulates VCIP135 function in Golgi membrane fusion during the cell cycle.Zhang X, Zhang H, Wang Y*.J Cell Sci. 2014;127(Pt1):172-81.Highlighted in “In

    This Issue”, Journal of Cell Science.

6. GRASPs in Golgi Structure and Function.Zhang X, Wang Y*.Front Cell Dev Biol. 2015;3:84.

7. Altered cofactor regulation with disease-associated p97/VCP mutations.Zhang X, Gui L, Zhang X, Bulfer SL, Sanghez V, Wong DE, Lee Y, Lehmann L, Lee JS, Shih PY, Lin

    HJ, Iacovino M, Weihl CC, Arkin MR, Wang Y, Chou TF*.Proc Natl Acad Sci U S A. 2015;112(14):E1705-14.

8. Cell cycle regulation of VCIP135 deubiquitinase activity and function in p97/p47-mediated Golgi reassembly.Zhang X, Wang Y*.Mol Biol Cell. 2015; 26(12): 2242-2251

9.Usp16 regulates kinetochore localization of Plk1 to promote proper chromosome alignment in mitosis. Zhuo X, Guo X, Zhang X, Jing G, Wang Y, Chen Q, Jiang Q, Liu J,

    Zhang C*.J Cell Biol. 2015;210(5):727-35.

10.Mena-GRASP65 interaction couples actin polymerization to Golgi ribbon linking. Tang D, Zhang X, Huang S, Yuan H, Li J, Wang Y*.Mol Biol Cell. 2016,27(1):137-52.

11. Glycosylation Quality Control by the Golgi Structure.Zhang X, Wang Y*.J Mol Biol. 2016; 428(16):3183-3193

12. Knockout of the Golgi stacking proteins GRASP55 and GRASP65 impairs Golgi structure and function.Bekier, M, Wang L, Li J, Huang H, Tang D, Zhang X, Wang Y*.

      Mol Biol Cell. 2017; 28(21):2833-2842.

13. GRASP55 senses glucose deprivation through O-GlcNAcylation to promote autophagosome-lysosome fusion.Zhang X*, Wang L, Lak B, Li J, Jokitalo E, Wang Y*.Dev Cell.

      2018;Apr 23;45(2):245-261.e6(* 共同通讯作者)

14. The Golgi stacking protein GORASP2/GRASP55 serves as an energy sensor to promote autophagosome maturation under glucose starvation.Zhang X*, Wang Y*.Autophagy

      2018;14(9):1649-1651(* 共同通讯作者)

15. GRASP55 facilitates autophagosome maturation under glucose deprivation. Zhang X*, Wang Y*.Molecular & Cellular Oncology 2018;e1494948(* 共同通讯作者)